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pathophysiology

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  Pathophysiology of Asthma:                                                            Asthma defination: Asthma is a chronic inflammatory disease of the airways in which variable periodic symptoms occurs, along with air flow obstruction,and bronchial hyper-responsiveness, is termed asthma. Types: 1.Extrinsic:This type is initiated by a type-1 hypersensitivity(atopic) response to an extrinsic antigen. 2.Intrinsic: This type is initiated by non-immune mechanisms,such as respiratory tract infections,exercise,aspirin,emotional upset and exposure to bronchial irritants Asthma was reclassified in to following type: 1.Atopic Asthma: This Asthma is of type I IgE-mediated hypersensitivity reaction.The attack of atopic asthma is caused by allergens in dust,pollen,animal dander,food etc. 2.Non-atopic Asthma: The asthmatic pateints do not show ...